Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA

Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA so?

agree, useful Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA

Adults: 80 to 100 mg I. Or, 120 mg P. Elderly patients: Reduced dosages may be indicated. Pharmacodynamics Diuretic action: Loop Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA inhibit sodium and chloride reabsorption in the Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA part of the ascending loop of Henle, promoting the excretion of sodium, water, chloride, and potassium. Antihypertensive action: This drug effect may be the result of renal and peripheral vasodilatation and a temporary increase in glomerular filtration rate and a decrease in peripheral vascular resistance.

Diuresis begins in 30 to 60 minutes and peaks 1 to 2 hours after oral administration. It crosses the placental barrier and appears in breast milk. Metabolism: Metabolized minimally by the liver. Duration of action is 6 to 8 hours after oral administration Rylaez about 2 hours after I. Contraindications and precautions Contraindicated in patients hypersensitive to drug Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA patients with anuria, hepatic coma, or severe electrolyte depletion.

Contraindicated if increased azotemia, oliguria, or progressive renal disease occur during therapy. Use cautiously in pregnant women, patients with sulfa allergy, and in lupus erythematosus with hepatic cirrhosis.

Aminoglycoside antibiotics, cisplatin, ethacrynic acid: May potentiate ototoxicity. Amphotericin B, corticosteroids, corticotropin, metolazone: Increases risk of hypokalemia. Antidiabetics: Decreases hypoglycemic effects. Antihypertensives: Increases Rykaze of hypotension.

Check blood pressure frequently. Cardiac glycosides, lithium, neuromuscular blockers: Increases risk of toxicity. NSAIDs: May inhibit diuretic response. Salicylates: May cause salicylate toxicity. Sucralfate: May reduce diuretic and antihypertensive effect. Separate administration by 2 hours. Aloe: May increase drug effects. Tell patient to use together cautiously. Dandelion: May interfere with diuretic activity.

Ginseng: Decreases effect of loop diuretic. Sun exposure: Potentiates photosensitivity reactions. Advise patient to uti symptoms precautions. Adverse reactionsCNS: vertigo, headache, dizziness, paresthesia, restlessness, (Recombiannt). CV: volume depletion and dehydration, orthostatic hypotension, thrombophlebitis with I. EENT: transient deafness with too-rapid I. GU: nocturia, azotemia, polyuria, frequent urination, renal failure, oliguria.

Hematologic: agranulocytosis, leukopenia, Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA, anemia, aplastic anemia. Musculoskeletal: muscle spasm, weakness. Skin: dermatitis, purpura, transient pain at I.

May decrease potassium, sodium, calcium, and magnesium levels. Overdose and treatment Signs and symptoms of overdose include profound electrolyte Rylaze (Asparaginase Erwinia Chrysanthemi (Recombinant) - rywn) Injection)- FDA volume depletion, which may precipitate circulatory collapse.

The usual pediatric dosage can be used, but extend dosing intervals. Excessive diuresis promotes rapid dehydration, leading to hypovolemia, hypokalemia, hyponatremia, and circulatory collapse. Explain that reaction is a photoallergy in which ultraviolet radiation alters drug structure, causing allergic reactions in some people. Click here for Health Professional Information NOTE: Your browser is not set to Ijnection)- our search feature.

Please either: - Use another browser - Adjust your browser settings to enable Javascript - Use the A-Z index at left to locate your drug Professional Medicine Information Search. Click here for Consumer Information Search The goal of the strategy is to make the best possible (Asparaginade of medicines to improve health outcomes for all Australians.

We support this goal giving providing free access to high quality, up to date information about medicines that are approved for use in Australia.



23.08.2019 in 17:18 pieteakysod:
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